Blar i forfatter "Kirov, Mikhail"

Viser treff 1-7 av 7

    • Comparison of Goal-Directed Hemodynamic Optimization using Pulmonary Artery Catheter and Transpulmonary Thermodilution in Combined Valve Repair: A Randomized Clinical Trial 

      Lenkin, A; Kirov, Mikhail; Kuzkov, Vsevolod; Paromov, KV; Smetkin, Alexey Anatolievich; Lie, Mons; Bjertnæs, Lars J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      Our aim was to compare the effects of goal-directed therapy guided either by pulmonary artery catheter (PAC) or by transpulmonary thermodilution (TTD) combined with monitoring of oxygen transport on perioperative hemodynamics and outcome after complex elective valve surgery. Measurements and Main Results. Forty patients were randomized into two equal groups: a PAC group and a TTD group. In the ...

    • Derecruitment Test and Surfactant Therapy in Patients with Acute Lung Injury. 

      Smetkin, Alexey Anatolievich; Kuzkov, Vsevolod; Gaidukov, Konstantin M; Bjertnæs, Lars J.; Kirov, Mikhail (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      A recruitment maneuver (RM) may improve gas exchange in acute lung injury (ALI). The aim of our study was to assess the predictive value of a derecruitment test in relation to RM and to evaluate the efficacy of RM combined with surfactant instillation in patients with ALI. Materials and Methods. Thirteen adult mechanically ventilated patients with ALI were enrolled into a prospective pilot study. ...

    • Epidural anesthesia and postoperative analgesia with ropivacaine and fentanyl in off-pump coronary artery bypass grafting: a randomized, controlled study 

      Kirov, Mikhail; Eremeev, Alexey; Smetkin, Alexey Anatolievich; Bjertnæs, Lars J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      Our aim was to assess the efficacy of thoracic epidural anesthesia (EA) followed by postoperative epidural infusion (EI) and patient-controlled epidural analgesia (PCEA) with ropivacaine/fentanyl in off-pump coronary artery bypass grafting (OPCAB). In a prospective study, 93 patients were scheduled for OPCAB under propofol/fentanyl anesthesia and randomized to three postoperative analgesia regimens ...

    • Increased Extravascular Lung Water reduces the Efficacy of Alveolar Recruitment Maneuver in Acute Respiratory Distress Syndrome. 

      Smetkin, Alexey Anatolievich; Kuzkov, Vsevolod; Suborov, Evgeny; Bjertnæs, Lars J.; Kirov, Mikhail (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      In acute respiratory distress syndrome (ARDS) the recruitment maneuver (RM) is used to reexpand atelectatic areas of the lungs aiming to improve arterial oxygenation. The goal of our paper was to evaluate the response to RM, as assessed by measurements of extravascular lung water index (EVLWI) in ARDS patients. Materials and Methods. Seventeen adult ARDS patients were enrolled into a prospective ...

    • Inhibitor of neuronal nitric oxide synthase improves gas exchange in ventilator-induced lung injury after pneumonectomy. 

      Suborov, Evgeny; Smetkin, Alexey Anatolievich; Kondratyev, Timofey; Valkov, Andrey Yurjevich; Kuzkov, Vsevolod; Kirov, Mikhail; Bjertnæs, Lars J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      Mechanical ventilation with high tidal volumes may cause ventilator-induced lung injury (VILI) and enhanced generation of nitric oxide (NO). We demonstrated in sheep that pneumonectomy followed by injurious ventilation promotes pulmonary edema. We wished both to test the hypothesis that neuronal NOS (nNOS), which is distributed in airway epithelial and neuronal tissues, could be involved in the ...

    • Measuring extravascular lung water. Animals and humans are not the same 

      Bjertnæs, Lars J.; Kirov, Mikhail; Kuzkov, Vsevolod V.; Fernandez-Mondejar, Enrique (Journal article; Tidsskriftartikkel; Peer reviewed, 2006-07-24)
      The evolution of extravascular lung water (EVLW) monitoring is an important step forward in the hemodynamic assessment of critically ill patients.

    • Physiological Changes in Subjects Exposed to Accidental Hypothermia: An Update 

      Bjertnaes, Lars J.; Næsheim, Torvind; Reierth, Eirik; Suborov, Evgeny; Kirov, Mikhail; Lebedinskii, Konstantin M.; Tveita, Torkjel (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-02-23)
      Background: Accidental hypothermia (AH) is an unintended decrease in body core temperature (BCT) to below 35°C. We present an update on physiological/pathophysiological changes associated with AH and rewarming from hypothermic cardiac arrest (HCA).<p> <p>Temperature Regulation and Metabolism: Triggered by falling skin temperature, Thyrotropin-Releasing Hormone (TRH) from hypothalamus induces ...